NFL Week 16 Betting Odds, Spreads, Tips & Predictions 2021 0:00 Intro 31:45 San Francisco 49ers at Tennessee Titans 8:20, FOX/NFL Network Line: San Francisco -3.5, o/u: 44.5 Saturday, December 25 35:00 Cleveland Browns at Green Bay Packers 4:30, FOX/NFL Network Line: Green Bay -7, o/u: 44.5 37:55 Indianapolis Colts at Arizona Cardinals 8:15, NFL Network Line: PICK, o/u: 49.5 Sunday, December 26 40:00 Detroit Lions at Atlanta Falcons 1:00, FOX Line: Atlanta -6, o/u: 42.5 45:15 Baltimore Ravens at Cincinnati Bengals 1:00, CBS Line: Cincinnati -2.5, o/u: 44.5 48:05 Los Angeles Rams at Minnesota Vikings 1:00, FOX Line: Los Angeles Rams -3, o/u: 49 50:32 Buffalo Bills at New England Patriots 1:00, CBS Line: New England -2.5, o/u: 43.5 52:48 Jacksonville Jaguars at New York Jets 1:00, CBS Line: New York Jets -2.5, o/u: 41.5 57:33 New York Giants at Philadelphia Eagles 1:00, FOX Line: Philadelphia -10, o/u: 41.5 1:00:14 Tampa Bay Buccaneers at Carolina Panthers 1:00, FOX Line: Tampa Bay -11, o/u: 44.5 1:04:00 Los Angeles Chargers at Houston Texans 4:05, CBS Line: Los Angeles Chargers -9.5, o/u: 45.5 1:05:55 Chicago Bears at Seattle Seahawks 4:05, FOX Line: Seattle -7, o/u: 44 1:10:30 Pittsburgh Steelers at Kansas City Chiefs 4:25, CBS Line: Kansas City -10, o/u: 46 1:13:20 Denver Broncos at Las Vegas Raiders 4:25, CBS Line: Las Vegas -1, o/u: 41.5 1:15:25 Washington Football Team at Dallas Cowboys 8:20, NBC Line: Dallas -10.5, o/u: 47 Monday, December 27 1:16:25 Miami Dolphins at New Orleans Saints 8:15, ESPN Line: New Orleans -3, o/u: 38.5 #TitanUp #49ers #NFL nfl week 16 betting odds,nfl picks,nfl week 16,nfl betting,nfl predictions,nfl odds,nfl week 16 picks,nfl week 16 predictions,nfl best bets,free nfl picks,week 16 nfl picks,nfl betting lines,nfl betting advice,week 16 nfl odds,week 16 picks,nfl picks week 16,nfl bets,nfl free picks,nfl week 16 predictions 2021,week 16 nfl predictions,nfl betting tips,nfl betting odds,nfl odds this week,nfl odds and lines,week 16 nfl,nfl betting strategy,nfl opening lines,nfl weekly picks,nfl bet picks Tampa Bay Buccaneers at Carolina Panthers 1:00, FOX Line: Tampa Bay -11, o/u: 44.5 Los Angeles Chargers at Houston Texans 4:05, CBS Line: Los Angeles Chargers -9.5, o/u: 45.5 Chicago Bears at Seattle Seahawks 4:05, FOX Line: Seattle -7, o/u: 44 Pittsburgh Steelers at Kansas City Chiefs 4:25, CBS Line: Kansas City -10, o/u: 46 Denver Broncos at Las Vegas Raiders 4:25, CBS Line: Las Vegas -1, o/u: 41.5 Washington Football Team at Dallas Cowboys 8:20, NBC Line: Dallas -10.5, o/u: 47 Monday, December 27 Miami Dolphins at New Orleans Saints 8:15, ESPN Line: New Orleans -3, o/u: 38.5