November 12, 2020, 8:20 pm EDT, Nissan Stadium, Nashville, Tenn. There is a good chance that the next three weeks decide the AFC South. The Tennessee Titans and Indianapolis Colts will collide twice during this stretch, first in Tennessee on Thursday Night Football and on Nov. 29 in Indianapolis. Right now the division is anyone’s ballgame—at least when it comes to the Titans and Colts. Rachael van Oranje and Jeff Reinebold from the Pickswise NFL Show give us their picks for Thursday Night Football! Full Week 10 picks video: https://youtu.be/MfGqgGCc1Gg Tennessee is coming off a much-needed win over the Chicago Bears (24-17). Derrick Henry and company had previously lost two in a row on the heels of a 5-0 start. Indianapolis, on the other hand, has been playing well since a slow start. It is 5-2 in its last seven outings despite falling to the Baltimore Ravens in Week 9. This should be a good one between two teams that are in the top 11 of our current power rankings. Be sure to check out our Colts vs Titans Thursday Night Football predictions for our expert handicapper’s picks, computer projections, and probabilities for the point spread, total, money line, and individual player performances. Thursday Night Football Betting Odds & Lines Preview Tennessee opened as a -2.5 favorite, briefly fell to as low as -1, and has settled in at -2. As the minor fluctuation but overall stagnation suggests, for many bettors this is a tough one to call. The two teams appear to be evenly matched—good, but not great. However, there could be some value on the Colts as underdogs. They played very well on defense against Lamar Jackson and the Ravens, simply doomed by a bit of bad luck in that contest. On the other side of the ball, Philip Rivers should have all day to throw the ball against a Titans defense that has one of the worst pass-rushes in the NFL. The total has been on a steady decline, albeit not a particularly steep one. It opened at 50.5 and has since dipped to 48.5. It makes sense that people are backing the under, mainly because Indy’s defense continued to excel last weekend against Baltimore and Tennessee’s offense has been sputtering. Both Henry and quarterback Ryan Tannehill have cooled off of late. Even at this lower number, the under may still be worth taking. What do you like in this game? Let us know in the comments!