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Nociception
Nociception is the sensory nervous system's process of encoding noxious stimuli. In nociception, intense chemical (e.g., cayenne powder), mechanical (e.g., cutting, crushing), or thermal (heat and cold) stimulation of sensory nerve cells called nociceptors produces a signal that travels along a chain of nerve fibers via the spinal cord to the brain.
Nociceptor
A nociceptor is a sensory neuron that responds to damaging or potentially damaging stimuli by sending “possible threat” signals to the spinal cord and the brain. If the brain perceives the threat as credible, it creates the sensation of pain to direct attention to the body part, so the threat can hopefully be mitigated; this process is called nociception.
Nociceptin
Nociceptin/orphanin FQ , a 17-amino acid neuropeptide, is the endogenous ligand for the nociceptin receptor (NOP, ORL-1), and initiates its function to act on numerous brain activities such as pain sensation and fear learning. It is derived from the prepronociceptin protein, as are a further 2 peptides, nocistatin & NocII, which inhibit the N/OFQ receptor function.
Nociceptin receptor
The nociceptin opioid peptide receptor , also known as the nociceptin/orphanin FQ (N/OFQ) receptor or kappa-type 3 opioid receptor, is a protein that in humans is encoded by the OPRL1 (opioid receptor-like 1) gene. The nociceptin receptor is a member of the opioid subfamily of G protein-coupled receptors whose natural ligand is the 17 amino acid neuropeptide known as nociceptin (N/OFQ).
Nuciferine
Nuciferine is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera. Preliminary psychopharmacological research in 1978 was unable to conclusively determine the compound's classification in regards to dopamine-receptor activity.On one hand, investigative studies found evidence of behavior traditionally associated with dopamine-receptor stimulation: stereotypy, increase in spontaneous motor activity, inhibition of conditioned avoidance response, and an increase in pain sensitivity resulting in an inhibition of morphine analgesia.On the other hand, these early investigative studies also found evidence of behavior traditionally associated with dopamine-receptor blockade: decrease of spontaneous motor activity, chills, catalepsy, trance-like states of consciousness.Nuciferine may also potentiate morphine analgesia.
Nučice (Prague-East District)
Nučice is a village and municipality in Prague-East District in the Central Bohemian Region of the Czech Republic.
Nučice (Prague-West District)
Nučice is a municipality and village in Prague-West District in the Central Bohemian Region of the Czech Republic. It has a population of about 2,200.
Nociception assay
A nociception assay evaluates the ability of an animal, usually a rodent, to detect a noxious stimulus such as the feeling of pain, caused by stimulation of nociceptors. These assays measure the existence of pain through behaviors such as withdrawal, licking, immobility, and vocalization.
Nucifer experiment
The Nucifer Experiment is a proposed test of equipment and methodologies for using neutrino detection for the monitoring of nuclear reactor activity and the assessment of the isotopic composition of reactor fuels for non-proliferation treaty compliance monitoring. Based upon an idea proposed by L.A. Mikaélyan in 1977, the Nucifer Experiment was proposed to the IAEA in October 2008.
Nucinellidae
Nucinellidae is a family of bivalves, in the order Solemyida. Its species are small and principally reside in deep-water environments.
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